STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sros_5052KEGG: hypothetical protein. (511 aa)    
Predicted Functional Partners:
Sros_7385
KEGG: rce:RC1_2762 HAD-superfamily hydrolase, subfamily IA.
      0.894
Sros_5916
KEGG: rpc:RPC_4133 HAD family hydrolase.
      0.887
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.871
nfo
Deoxyribonuclease IV (phage-T(4)-induced); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
    
 
 0.869
Sros_9360
KEGG: sfu:Sfum_0659 apurinic endonuclease Apn1.
    
 
 0.869
Sros_1317
KEGG: rru:Rru_A3357 transcriptional regulator Ada / DNA-3-methyladenine glycosylase II / DNA-O6-methylguanine-- protein-cysteine S-methyltransferase.
  
 0.860
nth
DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 0.844
Sros_9146
A/G-specific DNA glycosylase-like protein; KEGG: msl:Msil_1600 A/G-specific adenine glycosylase.
    
 0.822
Sros_0272
KEGG: hypothetical protein; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
 
 0.806
Sros_5853
DNA polymerase I; KEGG: pca:Pcar_2864 DNA polymerase I.
  
 0.802
Your Current Organism:
Streptosporangium roseum
NCBI taxonomy Id: 479432
Other names: S. roseum DSM 43021, Streptosporangium roseum DSM 43021, Streptosporangium roseum str. DSM 43021, Streptosporangium roseum strain DSM 43021
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.