node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sros_8038 | Sros_8042 | Sros_8038 | Sros_8042 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | 0.888 |
Sros_8038 | Sros_8058 | Sros_8038 | Sros_8058 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. | 0.964 |
Sros_8038 | Sros_9103 | Sros_8038 | Sros_9103 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: msl:Msil_2816 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. | 0.923 |
Sros_8038 | edd | Sros_8038 | Sros_3373 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.622 |
Sros_8038 | ilvC | Sros_8038 | Sros_8057 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.883 |
Sros_8038 | ilvD | Sros_8038 | Sros_7332 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.977 |
Sros_8038 | leuA | Sros_8038 | Sros_2310 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.903 |
Sros_8038 | leuA-2 | Sros_8038 | Sros_3794 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.903 |
Sros_8038 | leuC | Sros_8038 | Sros_8018 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.991 |
Sros_8038 | leuD | Sros_8038 | Sros_8017 | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.986 |
Sros_8042 | Sros_8038 | Sros_8042 | Sros_8038 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | KEGG: scl:sce3734 putative alpha- isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.888 |
Sros_8042 | Sros_8058 | Sros_8042 | Sros_8058 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | KEGG: gur:Gura_3719 acetolactate synthase 3 regulatory subunit. | 0.996 |
Sros_8042 | Sros_9103 | Sros_8042 | Sros_9103 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | KEGG: msl:Msil_2816 thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. | 0.607 |
Sros_8042 | edd | Sros_8042 | Sros_3373 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. | 0.923 |
Sros_8042 | ilvC | Sros_8042 | Sros_8057 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.982 |
Sros_8042 | ilvD | Sros_8042 | Sros_7332 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | KEGG: nmn:NMCC_1068 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.956 |
Sros_8042 | leuA | Sros_8042 | Sros_2310 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.880 |
Sros_8042 | leuA-2 | Sros_8042 | Sros_3794 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.894 |
Sros_8042 | leuC | Sros_8042 | Sros_8018 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.999 |
Sros_8042 | leuD | Sros_8042 | Sros_8017 | KEGG: sfu:Sfum_3031 isocitrate/isopropylmalate dehydrogenase. | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.999 |