STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
acsAacetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)    
Predicted Functional Partners:
Caci_6150
PFAM: Citrate synthase; KEGG: sma:SAV_2427 citrate synthase; Belongs to the citrate synthase family.
  
 0.956
Caci_8787
PFAM: Citrate synthase; KEGG: sma:SAV_3859 citrate synthase 2; Belongs to the citrate synthase family.
  
 0.956
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.955
Caci_7671
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: sma:SAV_4877 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.951
Caci_6197
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.947
Caci_0798
PFAM: Aldehyde Dehydrogenase; KEGG: nca:Noca_3529 aldehyde dehydrogenase (acceptor).
  
 0.934
Caci_2132
PFAM: Aldehyde Dehydrogenase; KEGG: sma:SAV_5852 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.934
Caci_4527
PFAM: Aldehyde Dehydrogenase; KEGG: sma:SAV_7177 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.934
Caci_7087
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: msm:MSMEG_2449 methylmalonate-semialdehyde dehydrogenase.
  
 0.934
Caci_7300
PFAM: Aldehyde Dehydrogenase; KEGG: sgr:SGR_5794 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.934
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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