Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Caci_0806PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: sco:SCO4919 flavoprotein disulfide reductase. (471 aa)    
Predicted Functional Partners:
Caci_1829
KEGG: sen:SACE_1638 dihydrolipoamide succinyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein.
 
 0.920
Caci_0091
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sco:SCO3815 branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.906
Caci_6169
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sco:SCO3829 branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.901
Caci_5067
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; KEGG: sco:SCO1268 acyltransferase.
 
 0.885
Caci_7565
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; KEGG: sco:SCO5281 alpha-ketoglutarate decarboxylase.
  
 0.869
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.854
Caci_6170
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sma:SAV_4363 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-beta chain.
 
 0.844
Caci_0092
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sco:SCO3816 branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 
 0.839
Caci_3260
PFAM: Transketolase central region; Transketolase domain protein; KEGG: saq:Sare_2669 transketolase central region.
 
 0.820
Caci_5068
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.819
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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