STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_1109PFAM: bifunctional deaminase-reductase domain protein; KEGG: sgr:SGR_4485 hypothetical protein. (190 aa)    
Predicted Functional Partners:
Caci_1110
PFAM: Activator of Hsp90 ATPase 1 family protein; KEGG: fra:Francci3_2808 hypothetical protein.
       0.782
Caci_1111
KEGG: rha:RHA1_ro07127 ArsR family transcriptional regulator.
       0.782
Caci_8364
PFAM: bifunctional deaminase-reductase domain protein; KEGG: rsa:RSal33209_1793 5-amino-6-(5- phosphoribosylamino)uracil reductase.
 
     0.652
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.620
Caci_1112
KEGG: hypothetical protein.
       0.508
Caci_1113
Hypothetical protein.
       0.508
Caci_1114
PFAM: alpha/beta hydrolase fold protein; KEGG: hau:Haur_4401 alpha/beta hydrolase fold protein.
  
    0.415
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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