STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_4591Hypothetical protein. (266 aa)    
Predicted Functional Partners:
Caci_7781
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: fre:Franean1_1091 acetolactate synthase 3 regulatory subunit.
  
 
 0.890
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.617
Caci_2296
KEGG: stp:Strop_1604 hypothetical protein.
  
  
 0.590
Caci_4820
KEGG: bur:Bcep18194_B0773 PEP phosphonomutase.
  
  
 0.590
Caci_0721
PFAM: alanine racemase domain protein; KEGG: nfa:nfa19290 hypothetical protein.
  
    0.578
Caci_2485
PFAM: alanine racemase domain protein; KEGG: sen:SACE_5299 D-amino acid deaminase.
  
    0.578
Caci_3481
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
 0.543
Caci_4592
Hypothetical protein.
       0.527
Caci_5702
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: sgr:SGR_5483 putative glutamate synthase (NADPH) large subunit.
  
  
 0.510
Caci_3637
PFAM: Catalase domain protein; KEGG: sma:SAV_2026 catalase; Belongs to the catalase family.
  
 0.443
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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