STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_4917KEGG: ssp:SSP0177 hypothetical protein. (426 aa)    
Predicted Functional Partners:
Caci_4914
PFAM: ExsB family protein; KEGG: fre:Franean1_0147 ExsB family protein.
 
  
 0.989
Caci_4916
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; KEGG: nca:Noca_0169 circadian phase modifier CpmA.
 
  
 0.989
larC
Protein of unknown function DUF111; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
  
 0.971
Caci_4408
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: mmi:MMAR_1816 L-lactate dehydrogenase (cytochrome) LldD1_1.
    
 0.905
Caci_4852
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: sen:SACE_5887 L-lactate dehydrogenase.
    
 0.905
Caci_1837
PFAM: beta-lactamase domain protein; KEGG: sus:Acid_0861 beta-lactamase domain- containing protein.
     
  0.900
Caci_2364
PFAM: beta-lactamase domain protein; KEGG: sco:SCO1509 hydrolase.
     
  0.900
Caci_4920
PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sma:SAV_7278 GntR family transcriptional regulator.
       0.780
Caci_4918
PFAM: amidohydrolase 2; KEGG: sma:SAV_7286 hypothetical protein.
       0.778
Caci_4919
5-carboxymethyl-2-hydroxymuconateDelta- isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sen:SACE_3938 putative 2-hydroxyhepta-2,4- diene-1,7-dioate isomerase.
       0.777
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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