STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_5069PFAM: dehydrogenase E1 component; KEGG: sco:SCO1270 pyruvate dehydrogenase alpha subunit. (320 aa)    
Predicted Functional Partners:
Caci_5068
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
Caci_0092
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sco:SCO3816 branched-chain alpha keto acid dehydrogenase E1 beta subunit.
 0.997
Caci_3260
PFAM: Transketolase central region; Transketolase domain protein; KEGG: saq:Sare_2669 transketolase central region.
 0.997
Caci_6170
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sma:SAV_4363 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) E1-beta chain.
 0.997
Caci_5067
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; KEGG: sco:SCO1268 acyltransferase.
 
 0.990
Caci_0091
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sco:SCO3815 branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.959
Caci_6169
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: sco:SCO3829 branched-chain alpha-keto acid dehydrogenase subunit E2.
 0.959
Caci_1829
KEGG: sen:SACE_1638 dihydrolipoamide succinyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein.
 0.950
Caci_5070
PFAM: phosphopantetheine-binding; condensation domain protein; KEGG: psb:Psyr_2608 amino acid adenylation.
 
     0.812
Caci_1830
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; FAD dependent oxidoreductase; KEGG: sgr:SGR_5330 putative dihydrolipoamide dehydrogenase.
 
 0.806
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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