node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Caci_0664 | Caci_1200 | Caci_0664 | Caci_1200 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.941 |
Caci_0664 | Caci_1610 | Caci_0664 | Caci_1610 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | 0.922 |
Caci_0664 | Caci_2716 | Caci_0664 | Caci_2716 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hsl:OE1807R threonine synthase. | 0.941 |
Caci_0664 | Caci_5175 | Caci_0664 | Caci_5175 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sgr:SGR_6518 putative aldolase. | 0.915 |
Caci_0664 | Caci_6417 | Caci_0664 | Caci_6417 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sma:SAV_3191 threonine synthase. | 0.945 |
Caci_0664 | Caci_8125 | Caci_0664 | Caci_8125 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sco:SCO4293 threonine synthase. | 0.941 |
Caci_0664 | gcvP | Caci_0664 | Caci_4780 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.441 |
Caci_0664 | glyA | Caci_0664 | Caci_1644 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.947 |
Caci_1200 | Caci_0664 | Caci_1200 | Caci_0664 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | 0.941 |
Caci_1200 | Caci_1610 | Caci_1200 | Caci_1610 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | 0.941 |
Caci_1200 | Caci_5175 | Caci_1200 | Caci_5175 | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sgr:SGR_6518 putative aldolase. | 0.925 |
Caci_1610 | Caci_0664 | Caci_1610 | Caci_0664 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: sma:SAV_3302 threonine dehydratase. | 0.922 |
Caci_1610 | Caci_1200 | Caci_1610 | Caci_1200 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.941 |
Caci_1610 | Caci_2716 | Caci_1610 | Caci_2716 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: hsl:OE1807R threonine synthase. | 0.941 |
Caci_1610 | Caci_5175 | Caci_1610 | Caci_5175 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sgr:SGR_6518 putative aldolase. | 0.915 |
Caci_1610 | Caci_6417 | Caci_1610 | Caci_6417 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sma:SAV_3191 threonine synthase. | 0.946 |
Caci_1610 | Caci_8125 | Caci_1610 | Caci_8125 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sco:SCO4293 threonine synthase. | 0.941 |
Caci_1610 | gcvP | Caci_1610 | Caci_4780 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.441 |
Caci_1610 | glyA | Caci_1610 | Caci_1644 | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: nfa:nfa44640 threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.947 |
Caci_2032 | Caci_2033 | Caci_2032 | Caci_2033 | Glycine cleavage system P-protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | KEGG: vei:Veis_2458 glycine dehydrogenase subunit 2. | 0.999 |