STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_5226PFAM: Uracil-DNA glycosylase superfamily; KEGG: sma:SAV_6242 hypothetical protein. (244 aa)    
Predicted Functional Partners:
Caci_8784
PFAM: Uracil-DNA glycosylase superfamily; KEGG: ace:Acel_0118 phage SPO1 DNA polymerase- related protein.
  
  
  0.916
Caci_2040
KEGG: sgr:SGR_5893 hypothetical protein.
      0.634
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
    
 0.618
Caci_5225
PFAM: glycoside hydrolase family 76; KEGG: sma:SAV_627 glycosyl hydrolase.
       0.561
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.559
Caci_1000
PFAM: peptidase M22 glycoprotease; KEGG: sco:SCO4750 hypothetical protein.
  
    0.519
Caci_5224
PFAM: Carbohydrate binding family 6; SMART: cellulose binding type IV; KEGG: hypothetical protein.
       0.488
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
 
    0.459
Caci_7615
KEGG: sma:SAV_5038 hypothetical protein.
 
   
 0.448
Caci_7937
KEGG: ace:Acel_1768 UBA/ThiF-type NAD/FAD binding protein.
  
  
 0.447
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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