STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
idiIsopentenyl-diphosphate delta-isomerase, type 1; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (181 aa)    
Predicted Functional Partners:
Caci_3312
PFAM: Polyprenyl synthetase; KEGG: sgr:SGR_6931 putative polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 0.991
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.970
Caci_1571
PFAM: Polyprenyl synthetase; KEGG: saq:Sare_3478 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
 0.969
Caci_0733
Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
 
 0.915
Caci_4971
PFAM: Polyprenyl synthetase; KEGG: sen:SACE_3979 dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.915
Caci_5921
PFAM: Polyprenyl synthetase; KEGG: sgr:SGR_2263 putative polyprenyl diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.915
Caci_6665
PFAM: Polyprenyl synthetase; KEGG: sen:SACE_4328 dimethylallyltranstransferase / geranyltranstransferase / geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.915
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
      
 0.715
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
      
 0.705
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
      
 0.701
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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