node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Caci_2900 | Caci_6429 | Caci_2900 | Caci_6429 | KEGG: cau:Caur_2944 hypothetical protein. | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | 0.870 |
Caci_2900 | clpB-2 | Caci_2900 | Caci_6431 | KEGG: cau:Caur_2944 hypothetical protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.745 |
Caci_2900 | grpE | Caci_2900 | Caci_0082 | KEGG: cau:Caur_2944 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.938 |
Caci_2900 | grpE-2 | Caci_2900 | Caci_6428 | KEGG: cau:Caur_2944 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.938 |
Caci_3458 | Caci_6429 | Caci_3458 | Caci_6429 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4601 non-ribosomal peptide synthase. | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | 0.926 |
Caci_4582 | Caci_6429 | Caci_4582 | Caci_6429 | Hypothetical protein; KEGG: sco:SCO3288 integral membrane protein. | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | 0.878 |
Caci_4582 | clpB-2 | Caci_4582 | Caci_6431 | Hypothetical protein; KEGG: sco:SCO3288 integral membrane protein. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.879 |
Caci_4582 | grpE | Caci_4582 | Caci_0082 | Hypothetical protein; KEGG: sco:SCO3288 integral membrane protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.957 |
Caci_4582 | grpE-2 | Caci_4582 | Caci_6428 | Hypothetical protein; KEGG: sco:SCO3288 integral membrane protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.957 |
Caci_6429 | Caci_2900 | Caci_6429 | Caci_2900 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | KEGG: cau:Caur_2944 hypothetical protein. | 0.870 |
Caci_6429 | Caci_3458 | Caci_6429 | Caci_3458 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4601 non-ribosomal peptide synthase. | 0.926 |
Caci_6429 | Caci_4582 | Caci_6429 | Caci_4582 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | Hypothetical protein; KEGG: sco:SCO3288 integral membrane protein. | 0.878 |
Caci_6429 | Caci_6430 | Caci_6429 | Caci_6430 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | KEGG: sma:SAV_7240 hypothetical protein. | 0.861 |
Caci_6429 | Caci_6432 | Caci_6429 | Caci_6432 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: rha:RHA1_ro06703 thioredoxin. | 0.942 |
Caci_6429 | clpB-2 | Caci_6429 | Caci_6431 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.910 |
Caci_6429 | dnaK | Caci_6429 | Caci_0081 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.975 |
Caci_6429 | dnaK-2 | Caci_6429 | Caci_6427 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.994 |
Caci_6429 | grpE | Caci_6429 | Caci_0082 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.884 |
Caci_6429 | grpE-2 | Caci_6429 | Caci_6428 | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.989 |
Caci_6430 | Caci_6429 | Caci_6430 | Caci_6429 | KEGG: sma:SAV_7240 hypothetical protein. | PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: sma:SAV_7239 heat shock protein DnaJ. | 0.861 |