STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Caci_7204TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; KEGG: cmi:CMM_0710 hypothetical protein. (105 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.967
Caci_2462
PFAM: Prephenate dehydrogenase; amino acid-binding ACT domain protein; KEGG: sgr:SGR_5738 putative prephenate dehydrogenase.
 
 0.945
Caci_6048
KEGG: sma:SAV_6086 2-dehydro-3- deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II; Belongs to the class-II DAHP synthase family.
 
 
 
 0.933
Caci_0097
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: ace:Acel_2105 prephenate dehydratase.
  
 
 0.922
Caci_3667
Anthranilate synthase; PFAM: Chorismate binding-like; KEGG: mka:MK0437 anthranilate/para-aminobenzoate synthase component I.
  
 
 0.913
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
  
 
 0.913
Caci_3668
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cau:Caur_1730 glutamine amidotransferase of anthranilate synthase.
  
 
 0.912
Caci_2461
TIGRFAM: chorismate mutase; PFAM: Chorismate mutase of the AroH class; KEGG: sma:SAV_6520 chorismate mutase.
     
 0.906
Caci_1021
KEGG: sco:SCO4784 hypothetical protein.
     
  0.900
Caci_0039
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: sgr:SGR_3722 putative glutamine amidotransferase.
  
 
 0.825
Your Current Organism:
Catenulispora acidiphila
NCBI taxonomy Id: 479433
Other names: C. acidiphila DSM 44928, Catenulispora acidiphila DSM 44928, Catenulispora acidiphila str. DSM 44928, Catenulispora acidiphila strain DSM 44928
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.