STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_0112PFAM: Thiolase; KEGG: rci:RCIX150 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)    
Predicted Functional Partners:
Sthe_1473
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: ttj:TTHA0890 putative 3-hydroxyacyl-CoA dehydrogenase.
  
 0.999
Sthe_2923
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: ank:AnaeK_0386 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 0.999
Sthe_0255
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: mmi:MMAR_1322 3-hydroxybutyryl-CoA dehydrogenase FadB3.
  
 0.978
Sthe_1202
PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; KEGG: chy:CHY_1292 3-hydroxybutyryl-CoA dehydrogenase.
  
 0.978
Sthe_0113
PFAM: protein of unknown function DUF35; KEGG: mth:MTH1398 hypothetical protein.
  
 
 0.968
Sthe_0539
PFAM: protein of unknown function DUF35; KEGG: pol:Bpro_5254 protein of unknown function DUF35.
 
 
 0.966
Sthe_1794
PFAM: acyl-CoA dehydrogenase domain protein; Acyl- CoA dehydrogenase type 2 domain; KEGG: bpy:Bphyt_6603 acyl-CoA dehydrogenase domain protein.
 
 0.965
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.935
Sthe_2025
PFAM: AMP-dependent synthetase and ligase; KEGG: pcl:Pcal_0155 AMP-dependent synthetase and ligase.
  
 
 0.935
Sthe_2381
PFAM: AMP-dependent synthetase and ligase; KEGG: sth:STH1025 acetyl-coenzyme A synthetase.
  
 
 0.935
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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