STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_0306PFAM: aminotransferase class-III; KEGG: rca:Rcas_1811 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)    
Predicted Functional Partners:
Sthe_1802
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.985
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.981
Sthe_2651
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: gur:Gura_1876 malonyl CoA-acyl carrier protein transacylase.
    
 0.890
Sthe_2541
TIGRFAM: acyl-CoA ligase (AMP-forming), exosortase system type 1 associated; PFAM: AMP-dependent synthetase and ligase; KEGG: net:Neut_1417 AMP-dependent synthetase and ligase.
 
    0.887
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.844
Sthe_0374
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: mpo:Mpop_0527 malonyl CoA-acyl carrier protein transacylase.
    
 0.769
Sthe_0307
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: cak:Caul_2372 gamma-glutamyltransferase.
       0.668
Sthe_2949
PFAM: protein of unknown function DUF162; protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: gsu:GSU1620 iron-sulfur cluster binding protein, putative.
   
    0.476
Sthe_0304
Hypothetical protein.
       0.472
Sthe_0305
Hypothetical protein.
       0.472
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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