STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (145 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.999
Sthe_0561
TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: mta:Moth_0747 flagellar hook-associated protein FlgL.
 
 
 0.969
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: chy:CHY_0971 flagellar hook-associated protein FlgK.
 
  
 0.957
Sthe_0582
PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: swo:Swol_0861 hypothetical protein.
 
  
 0.901
Sthe_0558
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.894
Sthe_0557
Hypothetical protein; KEGG: cti:RALTA_B2129 FlaG: flagellar protein.
  
    0.884
Sthe_0555
TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; KEGG: tpd:Teth39_1770 flagellar protein FliS.
 
  
 0.860
Sthe_0556
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.848
Sthe_0552
TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_0463 flagellar basal-body rod protein FlgC.
 
 
 0.762
Sthe_0564
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: psb:Psyr_3488 anti-sigma-28 factor, FlgM.
  
  
 0.753
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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