STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_0674TIGRFAM: sulfate transporter; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; KEGG: amr:AM1_D0254 sulfate permease. (591 aa)    
Predicted Functional Partners:
Sthe_0300
KEGG: mgm:Mmc1_3623 proton-translocating NADH- quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I).
  
 
 0.784
Sthe_0102
KEGG: dde:Dde_3623 Ser/Thr protein phosphatase family protein.
  
   0.701
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
   0.701
Sthe_2590
PFAM: metallophosphoesterase; KEGG: aeh:Mlg_0828 metallophosphoesterase.
  
   0.701
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
   0.695
Sthe_2540
KEGG: pca:Pcar_2651 acyl-carrier protein.
    
   0.695
Sthe_1332
NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: rxy:Rxyl_1800 NADH dehydrogenase (quinone).
 
  
 0.680
Sthe_3126
PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: dol:Dole_2292 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.573
Sthe_0870
TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: krh:KRH_20580 DASS family transporter.
 
  
 0.516
Sthe_1128
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mbb:BCG_0370 putative dehydrogenase/reductase.
 
  
 0.495
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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