close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_1069PFAM: Xylose isomerase domain protein TIM barrel; KEGG: rci:RCIX603 hypothetical protein. (288 aa)    
Predicted Functional Partners:
Sthe_0357
PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: Animal peptidoglycan recognition protein PGRP; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: rca:Rcas_3535 hypothetical protein.
  
     0.615
Sthe_1071
PFAM: beta-lactamase domain protein; KEGG: fre:Franean1_3962 beta-lactamase domain- containing protein.
 
     0.604
Sthe_1141
PFAM: oxidoreductase domain protein; Oxidoreductase domain; dihydrodipicolinate reductase; KEGG: cau:Caur_1630 oxidoreductase domain- containing protein.
  
  
 0.604
Sthe_1362
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: jan:Jann_4111 oxidoreductase-like.
  
  
 0.604
Sthe_2759
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: bph:Bphy_1594 oxidoreductase domain- containing protein.
  
  
 0.604
Sthe_1576
KEGG: rrs:RoseRS_1626 hypothetical protein.
  
     0.584
Sthe_0399
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: fre:Franean1_1305 ABC transporter related.
  
     0.565
Sthe_1070
PFAM: peptidase S58 DmpA; KEGG: ajs:Ajs_2605 peptidase S58, DmpA.
       0.527
Sthe_1072
PFAM: Phosphoglycerate mutase; KEGG: dge:Dgeo_1615 phosphoglycerate mutase.
       0.527
Sthe_0921
KEGG: rrs:RoseRS_3193 hypothetical protein.
  
    0.520
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
Server load: medium (48%) [HD]