node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sthe_1259 | Sthe_1261 | Sthe_1259 | Sthe_1261 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | 0.751 |
Sthe_1259 | infB | Sthe_1259 | Sthe_1257 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.817 |
Sthe_1259 | nusA | Sthe_1259 | Sthe_1255 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.520 |
Sthe_1259 | rbfA | Sthe_1259 | Sthe_1258 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.982 |
Sthe_1259 | truB | Sthe_1259 | Sthe_1260 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.916 |
Sthe_1261 | Sthe_1259 | Sthe_1261 | Sthe_1259 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | 0.751 |
Sthe_1261 | infB | Sthe_1261 | Sthe_1257 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.682 |
Sthe_1261 | nusA | Sthe_1261 | Sthe_1255 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.561 |
Sthe_1261 | rbfA | Sthe_1261 | Sthe_1258 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.857 |
Sthe_1261 | truB | Sthe_1261 | Sthe_1260 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.989 |
guaA | infB | Sthe_1364 | Sthe_1257 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.812 |
guaA | nusA | Sthe_1364 | Sthe_1255 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | NusA antitermination factor; Participates in both transcription termination and antitermination. | 0.596 |
guaA | pnp | Sthe_1364 | Sthe_1553 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.868 |
guaA | rimM | Sthe_1364 | Sthe_1868 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.965 |
guaA | rpoC | Sthe_1364 | Sthe_1030 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.965 |
guaA | rpsO | Sthe_1364 | Sthe_1554 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.766 |
guaA | truB | Sthe_1364 | Sthe_1260 | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.985 |
infB | Sthe_1259 | Sthe_1257 | Sthe_1259 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mta:Moth_1052 phosphoesterase, RecJ-like. | 0.817 |
infB | Sthe_1261 | Sthe_1257 | Sthe_1261 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; cytidylyltransferase; Riboflavin kinase; KEGG: rsa:RSal33209_0668 FMN adenylyltransferase; Belongs to the ribF family. | 0.682 |
infB | guaA | Sthe_1257 | Sthe_1364 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.812 |