STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_1533PFAM: aldo/keto reductase; KEGG: saq:Sare_4281 aldo/keto reductase. (316 aa)    
Predicted Functional Partners:
Sthe_3124
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: hypothetical protein; K09876 aquaporin-3; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.724
Sthe_1534
Alkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
  
    0.662
Sthe_1318
Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
 
 0.579
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
  
 0.428
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
   0.406
Sthe_0656
KEGG: rrs:RoseRS_2563 hypothetical protein.
    
   0.400
Sthe_1682
PFAM: Protein phosphatase 2C-like; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: rrs:RoseRS_4547 protein phosphatase 2C domain- containing protein.
    
   0.400
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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