STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_1551Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; KEGG: rxy:Rxyl_0159 periplasmic sensor signal transduction histidine kinase. (437 aa)    
Predicted Functional Partners:
Sthe_1552
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rxy:Rxyl_0160 two component transcriptional regulator, LuxR family.
   0.965
Sthe_3241
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: xca:xccb100_2001 two-component system regulatory protein, LuxR family.
 
   0.900
Sthe_1615
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rca:Rcas_1579 two component LuxR family transcriptional regulator.
 
   0.876
Sthe_0243
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: cau:Caur_3230 response regulator receiver.
 
   0.866
Sthe_0200
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: gtn:GTNG_3075 two-component response regulator.
 
   0.865
Sthe_0608
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: response regulator receiver; regulatory protein LuxR; KEGG: ttj:TTHA1352 response regulator.
 
   0.862
Sthe_0155
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; Sigma-70 region 4 type 2; Bacterio-opsin activator HTH domain protein; SMART: response regulator receiver; regulatory protein LuxR; KEGG: sth:STH923 two-component response regulator.
 
   0.855
Sthe_1366
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; KEGG: rca:Rcas_1579 two component LuxR family transcriptional regulator.
 
   0.852
Sthe_0867
Two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: regulatory protein LuxR; response regulator receiver; KEGG: rrs:RoseRS_0938 two component LuxR family transcriptional regulator.
 
   0.849
Sthe_3218
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; KEGG: ank:AnaeK_0902 two component transcriptional regulator, LuxR family.
 
   0.836
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.