STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_1574KEGG: det:DET0328 hypothetical protein. (393 aa)    
Predicted Functional Partners:
Sthe_1573
KEGG: det:DET0327 hypothetical protein.
 
     0.958
Sthe_0991
PFAM: protein of unknown function DUF87; KEGG: rrs:RoseRS_1701 hypothetical protein.
 
 
 
 0.952
Sthe_1850
PFAM: SMC domain protein; Rad50 zinc hook domain protein; KEGG: rca:Rcas_4093 SMC domain-containing protein.
 
   
 0.821
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
     0.783
Sthe_1225
PFAM: PBS lyase HEAT domain protein repeat- containing protein; SMART: PBS lyase HEAT domain protein repeat- containing protein; KEGG: cau:Caur_2342 heat repeat-containing PBS lyase.
  
     0.755
Sthe_3405
Hypothetical protein.
  
     0.722
Sthe_1576
KEGG: rrs:RoseRS_1626 hypothetical protein.
 
     0.621
Sthe_2100
PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: hau:Haur_2733 VanW family protein.
  
     0.615
Sthe_1575
Hypothetical protein.
       0.608
Sthe_0335
PFAM: SCP-like extracellular; KEGG: cau:Caur_3540 hypothetical protein.
  
     0.601
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.