STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_1744PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: esi:Exig_3026 2-alkenal reductase. (282 aa)    
Predicted Functional Partners:
Sthe_3216
PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: aeh:Mlg_2213 peptidase S1 and S6, chymotrypsin/Hap.
  
  
 
0.929
Sthe_3346
HtrA2 peptidase; KEGG: pca:Pcar_2948 serine endoprotease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
  
  
 
0.925
Sthe_1745
Hypothetical protein; KEGG: Y47G6A.17.
       0.773
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.555
Sthe_1746
PFAM: Helix-turn-helix type 11 domain protein; KEGG: sfu:Sfum_2823 putative transcriptional regulator.
       0.524
Sthe_0685
KEGG: sth:STH1151 hypothetical protein.
   
  0.422
Sthe_0464
KEGG: sus:Acid_7135 putative membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.409
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.