STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: mta:Moth_1244 glutamate-1-semialdehyde 2,1- aminomutase. (427 aa)    
Predicted Functional Partners:
Sthe_1802
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mta:Moth_1246 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.995
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.994
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.963
Sthe_2651
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: gur:Gura_1876 malonyl CoA-acyl carrier protein transacylase.
    
 0.896
Sthe_1803
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.881
Sthe_2541
TIGRFAM: acyl-CoA ligase (AMP-forming), exosortase system type 1 associated; PFAM: AMP-dependent synthetase and ligase; KEGG: net:Neut_1417 AMP-dependent synthetase and ligase.
 
    0.871
Sthe_0374
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: mpo:Mpop_0527 malonyl CoA-acyl carrier protein transacylase.
    
 0.794
Sthe_0644
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.570
Sthe_0843
PFAM: aminotransferase class I and II; KEGG: mbu:Mbur_0428 aspartate aminotransferase.
   
  
 0.502
Sthe_2604
PFAM: aminotransferase class I and II; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: fph:Fphi_0426 aspartate aminotransferase.
   
  
 0.502
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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