STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_2011TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: pth:PTH_0822 septum formation inhibitor- activating ATPase. (287 aa)    
Predicted Functional Partners:
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
 
 0.999
minE
Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
 
 
 0.998
Sthe_2014
TIGRFAM: rod shape-determining protein MreD; KEGG: hmo:HM1_2728 rod shape-determining protein, putative.
  
  
 0.899
Sthe_0144
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
    0.831
Sthe_2009
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: afu:AF2218 hypothetical protein.
  
    0.799
accA-2
acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
    0.646
Sthe_0143
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; KEGG: rrs:RoseRS_1283 cell shape determining protein MreB.
 
 
 0.605
Sthe_2367
TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; KEGG: cau:Caur_3039 cell shape determining protein MreB.
 
 
 0.567
Sthe_2013
Penicillin-binding protein 2; KEGG: cau:Caur_0113 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
     
 0.565
Sthe_2008
KEGG: hau:Haur_4552 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
       0.467
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.