STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_2031Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: afw:Anae109_1498 GAF sensor signal transduction histidine kinase. (383 aa)    
Predicted Functional Partners:
Sthe_1941
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pth:PTH_0048 response regulator.
   0.960
Sthe_0369
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: lac:LBA0078 putative response regulator.
   0.910
Sthe_2197
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: hau:Haur_0905 two component transcriptional regulator.
   0.902
Sthe_2666
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: afw:Anae109_3104 two component transcriptional regulator.
   0.889
Sthe_2027
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sth:STH415 two-component response regulator.
   0.886
Sthe_3273
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: smd:Smed_5362 two component transcriptional regulator.
   0.838
Sthe_0648
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: afw:Anae109_1850 response regulator receiver protein.
 
   0.832
Sthe_2252
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: afw:Anae109_2598 response regulator receiver protein.
 
   0.832
Sthe_2441
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mxa:MXAN_2962 response regulator.
 
   0.832
Sthe_2675
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: lhk:LHK_00225 BaeR.
 
   0.832
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.