STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_2068PFAM: Luciferase-like monooxygenase; KEGG: msm:MSMEG_3301 hypothetical protein. (282 aa)    
Predicted Functional Partners:
Sthe_2500
TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; KEGG: cps:CPS_4045 putative F420-dependent oxidoreductase.
 
   
 0.756
Sthe_2613
TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: eba:p2A344 LPPG:FO 2-phospho-L-lactate transferase.
 
     0.754
fbiD
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
 
   
 0.735
Sthe_0529
PFAM: Luciferase-like monooxygenase; KEGG: rrs:RoseRS_1121 luciferase family protein.
  
     0.715
Sthe_3510
KEGG: xac:XAC3548 outer membrane protein.
  
     0.690
Sthe_2067
KEGG: rca:Rcas_3573 hypothetical protein.
 
     0.601
Sthe_2382
KEGG: rha:RHA1_ro03458 hypothetical protein.
  
     0.555
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
      
 0.501
Sthe_2501
TIGRFAM: PPOX class probable F420-dependent enzyme; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN- binding; KEGG: tbd:Tbd_0006 hypothetical protein.
  
     0.499
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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