STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_3485Mg-chelatase subunit ChlI-like protein; KEGG: CHLI1; CHLI1 (CHLORINA 42); magnesium chelatase; K03405 magnesium chelatase subunit ChlI. (465 aa)    
Predicted Functional Partners:
Sthe_3486
SMART: von Willebrand factor type A; KEGG: hypothetical protein.
    0.979
Sthe_2327
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
   
 
 0.920
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.919
Sthe_2947
KEGG: tmz:Tmz1t_0141 protoporphyrinogen oxidase.
     
  0.900
Sthe_0179
PFAM: ATPase associated with various cellular activities AAA_5; ATPase associated with various cellular activities AAA_3; von Willebrand factor type A; SMART: von Willebrand factor type A; KEGG: rxy:Rxyl_3152 ATPase associated with various cellular activities, AAA_5.
  
 
 0.825
Sthe_2861
PFAM: ATPase associated with various cellular activities AAA_5; ATPase associated with various cellular activities AAA_3; von Willebrand factor type A; SMART: von Willebrand factor type A; AAA ATPase; KEGG: mxa:MXAN_2475 putative transcriptional regulator.
  
 
 0.825
Sthe_3487
Hypothetical protein.
       0.625
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.576
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
 0.572
Sthe_3488
Hypothetical protein.
       0.542
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.