STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sthe_3492PFAM: biotin/lipoate A/B protein ligase; KEGG: bbr:BB2891 putative lipoate-protein ligase A. (260 aa)    
Predicted Functional Partners:
Sthe_3493
KEGG: oan:Oant_2218 biotin/lipoate A/B protein ligase.
     0.994
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 
 0.861
Sthe_3478
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide- disulphide oxidoreductase; glucose-inhibited division protein A; KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase.
 
 
 0.739
Sthe_3475
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: rpb:RPB_0277 dihydrolipoamide acetyltransferase.
 
 0.596
Sthe_2057
2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.593
Sthe_3226
PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; KEGG: pag:PLES_07751 branched-chain alpha-keto acid dehydrogenase subunit E2.
  
 0.572
Sthe_1933
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: rrs:RoseRS_1726 dihydrolipoyllysine-residue succinyltransferase.
  
 0.538
Sthe_3494
Transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: bxe:Bxe_B2360 GntR family transcriptional regulator.
       0.523
Sthe_3491
PFAM: glycosyl transferase group 1; KEGG: cja:CJA_0616 glycosyl transferase, putative, gt4J.
  
    0.476
Sthe_0229
PFAM: Transketolase central region; Transketolase domain protein; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide).
  
 
 0.436
Your Current Organism:
Sphaerobacter thermophilus
NCBI taxonomy Id: 479434
Other names: S. thermophilus DSM 20745, Sphaerobacter thermophilus DSM 20745, Sphaerobacter thermophilus str. DSM 20745, Sphaerobacter thermophilus strain DSM 20745
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