STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kfla_1414PFAM: Uroporphyrinogen III synthase HEM4; transcriptional regulator domain protein; KEGG: scl:sce6449 putative transcriptional regulator. (375 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.987
Kfla_3675
TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bpe:BP1055 siroheme synthase.
 
 
 0.970
Kfla_1412
TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta- component ferrodoxin domain protein; KEGG: rpi:Rpic_4164 nitrite reductase (NAD(P)H), large subunit.
 
  
 0.965
Kfla_1415
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: scl:sce0245 sirohydrochlorin cobaltochelatase.
 
  
 0.961
Kfla_1413
TIGRFAM: nitrite reductase [NAD(P)H], small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: scl:sce8493 nitrite reductase (NAD(P)H).
 
  
 0.952
Kfla_1410
PFAM: major facilitator superfamily MFS_1; KEGG: bja:blr2806 nitrite extrusion protein.
 
  
 0.949
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.936
Kfla_6374
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sfu:Sfum_3201 uroporphyrin-III C- methyltransferase.
 
 
 0.935
Kfla_1411
PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide- binding region; KEGG: msl:Msil_3772 molybdopterin oxidoreductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
   
 0.932
Kfla_6373
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sat:SYN_02267 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
 
 0.830
Your Current Organism:
Kribbella flavida
NCBI taxonomy Id: 479435
Other names: K. flavida DSM 17836, Kribbella flavida DSM 17836, Kribbella flavida str. DSM 17836, Kribbella flavida strain DSM 17836
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