STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kfla_1625Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: ank:AnaeK_3001 integral membrane sensor signal transduction histidine kinase. (545 aa)    
Predicted Functional Partners:
Kfla_1624
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sat:SYN_00981 response regulator.
 0.993
Kfla_1626
Hypothetical protein.
  
 0.983
Kfla_3900
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: avn:Avin_14320 periplasmic sensory histidine protein kinase.
 
 
0.927
Kfla_1015
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: gme:Gmet_2693 two component transcriptional regulator.
 
 0.811
Kfla_5788
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: ank:AnaeK_3000 two component transcriptional regulator, winged helix family.
 
 0.804
Kfla_6884
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: pca:Pcar_3081 two component signal transduction response regulator.
 
 0.803
Kfla_3436
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: psa:PST_2712 transcriptional activator CopR.
 
 0.797
Kfla_4457
Multi-sensor signal transduction histidine kinase; KEGG: scl:sce0206 two-component system sensor histidine kinase/response regulator, hybrid ('one- component system'); TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; response regulator receiver; PAS fold domain protein; PAS fold-4 domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; protein phosphatase 2C domain protein; PAC repeat-containing protein; histidine kinase A domain protein; PAS domain containing protein; ATP-binding region A [...]
  
 
0.793
Kfla_7039
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: scl:sce4878 two-component response regulator.
 
 0.789
Kfla_1375
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfu:Sfum_2007 two component transcriptional regulator, winged helix family.
 
 0.766
Your Current Organism:
Kribbella flavida
NCBI taxonomy Id: 479435
Other names: K. flavida DSM 17836, Kribbella flavida DSM 17836, Kribbella flavida str. DSM 17836, Kribbella flavida strain DSM 17836
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.