STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kfla_2036PFAM: metallophosphoesterase; KEGG: bcm:Bcenmc03_6434 metallophosphoesterase. (293 aa)    
Predicted Functional Partners:
cpdA
Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 
0.925
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.908
Kfla_0317
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: met:M446_0921 adenylate/guanylate cyclase.
     
 0.907
Kfla_0971
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: scl:sce7039 putative 5'-nucleotidase family protein; Belongs to the 5'-nucleotidase family.
   
 
 0.906
Kfla_3631
Adenylate/guanylate cyclase with integral membrane sensor; PFAM: histidine kinase HAMP region domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: histidine kinase HAMP region domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: bba:Bd1116 adenylate cyclase.
     
 0.906
Kfla_2653
PFAM: PfkB domain protein; KEGG: hha:Hhal_1195 ribokinase-like domain- containing protein.
    
  0.901
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.901
Kfla_1207
PFAM: Survival protein SurE; KEGG: aha:AHA_0826 acid phosphatase SurE.
     
  0.900
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Kfla_3445
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mxa:MXAN_2886 HAD family hydrolase.
    
  0.900
Your Current Organism:
Kribbella flavida
NCBI taxonomy Id: 479435
Other names: K. flavida DSM 17836, Kribbella flavida DSM 17836, Kribbella flavida str. DSM 17836, Kribbella flavida strain DSM 17836
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