STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kfla_3076PFAM: metallophosphoesterase; KEGG: met:M446_1703 metallophosphoesterase. (516 aa)    
Predicted Functional Partners:
Kfla_0121
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: rso:RS05070 putative hemagglutinin/hemolysin- related protein.
  
     0.733
Kfla_3308
Hypothetical protein.
  
     0.728
Kfla_1848
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.706
Kfla_2543
Hypothetical protein; KEGG: similar to lysyl oxidase-like protein; K00280.
  
     0.702
Kfla_3703
Hypothetical protein; KEGG: acp:A2cp1_3940 TPR repeat-containing protein.
  
     0.699
Kfla_4990
KEGG: SNF2 superfamily protein.
  
     0.620
Kfla_3087
PFAM: GCN5-related N-acetyltransferase; KEGG: rsp:RSP_3586 putative aromatic pathway regulator.
  
     0.553
Kfla_2734
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: sde:Sde_3605 glycosyl hydrolase family chitinase.
  
     0.550
Kfla_2124
PFAM: HI0933 family protein; KEGG: mxa:MXAN_0926 hypothetical protein.
 
     0.541
Kfla_2735
PFAM: PKD domain containing protein; SMART: PKD domain containing protein; KEGG: mxa:MXAN_5269 lysyl endopeptidase domain- containing protein.
  
     0.535
Your Current Organism:
Kribbella flavida
NCBI taxonomy Id: 479435
Other names: K. flavida DSM 17836, Kribbella flavida DSM 17836, Kribbella flavida str. DSM 17836, Kribbella flavida strain DSM 17836
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.