node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Elen_0618 | Elen_1347 | Elen_0618 | Elen_1347 | PFAM: aminotransferase class V; KEGG: rru:Rru_A1068 aminotransferase, class V. | PFAM: aminotransferase class V; KEGG: mgm:Mmc1_3063 aminotransferase, class V. | 0.921 |
Elen_0618 | thiI | Elen_0618 | Elen_1658 | PFAM: aminotransferase class V; KEGG: rru:Rru_A1068 aminotransferase, class V. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.963 |
Elen_1347 | Elen_0618 | Elen_1347 | Elen_0618 | PFAM: aminotransferase class V; KEGG: mgm:Mmc1_3063 aminotransferase, class V. | PFAM: aminotransferase class V; KEGG: rru:Rru_A1068 aminotransferase, class V. | 0.921 |
Elen_1347 | thiI | Elen_1347 | Elen_1658 | PFAM: aminotransferase class V; KEGG: mgm:Mmc1_3063 aminotransferase, class V. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.967 |
Elen_1347 | tsaD | Elen_1347 | Elen_2854 | PFAM: aminotransferase class V; KEGG: mgm:Mmc1_3063 aminotransferase, class V. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.421 |
Elen_1659 | Elen_1661 | Elen_1659 | Elen_1661 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Hypothetical protein. | 0.950 |
Elen_1659 | Elen_1711 | Elen_1659 | Elen_1711 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.802 |
Elen_1659 | gmk | Elen_1659 | Elen_1660 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.976 |
Elen_1659 | thiI | Elen_1659 | Elen_1658 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.633 |
Elen_1659 | tsaD | Elen_1659 | Elen_2854 | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.402 |
Elen_1661 | Elen_1659 | Elen_1661 | Elen_1659 | Hypothetical protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.950 |
Elen_1661 | gmk | Elen_1661 | Elen_1660 | Hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.864 |
Elen_1661 | thiI | Elen_1661 | Elen_1658 | Hypothetical protein. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.519 |
Elen_1711 | Elen_1659 | Elen_1711 | Elen_1659 | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.802 |
Elen_1711 | gmk | Elen_1711 | Elen_1660 | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.627 |
Elen_1711 | rlmL | Elen_1711 | Elen_1312 | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.706 |
Elen_1711 | thiI | Elen_1711 | Elen_1658 | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.893 |
Elen_1711 | tsaD | Elen_1711 | Elen_2854 | PFAM: NusB/RsmB/TIM44; Fmu (Sun) domain protein; KEGG: ppd:Ppro_3242 sun protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.627 |
Elen_1747 | Elen_1748 | Elen_1747 | Elen_1748 | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | TIGRFAM: thiamine biosynthesis protein ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: pca:Pcar_0611 thiamine biosynthesis protein ThiF. | 0.939 |
Elen_1747 | thiI | Elen_1747 | Elen_1658 | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.927 |