STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Elen_1720TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: dvm:DvMF_2650 phosphodiesterase, MJ0936 family. (182 aa)    
Predicted Functional Partners:
Elen_1719
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: dol:Dole_1124 metal-dependent phosphohydrolase.
       0.689
Elen_0217
TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: bsu:BSU00580 hypothetical protein.
 
    0.653
Elen_1954
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.607
Elen_2301
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.513
Elen_1951
TIGRFAM: DNA ligase D; DNA polymerase LigD, ligase domain protein; DNA polymerase LigD, polymerase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase; DNA primase small subunit; ATP dependent DNA ligase domain protein; KEGG: sme:SMc03959 hypothetical protein.
   
 
 0.468
tsaD
Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
     
 0.407
Your Current Organism:
Eggerthella lenta
NCBI taxonomy Id: 479437
Other names: E. lenta DSM 2243, Eggerthella lenta DSM 2243, Eggerthella lenta str. DSM 2243, Eggerthella lenta strain DSM 2243
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