STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Elen_2072TIGRFAM: siroheme synthase; KEGG: sat:SYN_02276 precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. (235 aa)    
Predicted Functional Partners:
Elen_2069
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dal:Dalk_4009 uroporphyrin-III C- methyltransferase.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.985
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gur:Gura_4245 glutamate-1-semialdehyde-2,1- aminomutase.
   
 0.960
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
   
 0.867
Elen_2067
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sfu:Sfum_3057 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
   
 0.841
Elen_2068
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sat:SYN_02268 radical SAM superfamily protein.
 
     0.825
Elen_2066
KEGG: sfu:Sfum_4037 putative transcriptional regulator, AsnC family.
 
   
 0.798
Elen_1856
PFAM: protein of unknown function DUF224 cysteine- rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sat:SYN_02638 iron-sulphur-binding reductase.
  
  
 0.556
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.452
Elen_2073
TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: sat:SYN_01522 thiamin pyrophosphokinase.
       0.436
Your Current Organism:
Eggerthella lenta
NCBI taxonomy Id: 479437
Other names: E. lenta DSM 2243, Eggerthella lenta DSM 2243, Eggerthella lenta str. DSM 2243, Eggerthella lenta strain DSM 2243
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