STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHMEG_00033518D-isomer specific 2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa)    
Predicted Functional Partners:
PHMEG_0002948
Tryptophan synthase, beta subunit.
  
 0.923
PHMEG_0002879
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.822
PHMEG_0002374
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.812
PHMEG_00015868
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.809
PHMEG_00014192
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.808
PHMEG_0008875
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.797
PHMEG_00014434
Acetolactate synthase.
  
 
 0.796
PHMEG_00027314
Malate synthase; Belongs to the malate synthase family.
    
 0.710
PHMEG_00010990
Hydroxyacylglutathione hydrolase.
    
 0.709
PHMEG_0005526
Hydroxyacylglutathione hydrolase.
    
 0.709
Your Current Organism:
Phytophthora megakarya
NCBI taxonomy Id: 4795
Other names: ATCC 42100, CBS 238.83, IMI 202077, P. megakarya
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