STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHMEG_0004776E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1989 aa)    
Predicted Functional Partners:
PHMEG_00015848
HECT E3 ubiquitin ligase.
   
 0.936
PHMEG_0007666
HECT E3 ubiquitin ligase.
   
 0.936
PHMEG_00017749
Ubiquitin-conjugating enzyme E2 2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.801
PHMEG_00025303
Ubiquitin family protein.
    
  0.675
PHMEG_00020723
Ubiquitin-like domain-containing protein.
    
  0.675
PHMEG_00014556
Ubiquitin-ribosomal fusion protein.
    
  0.675
PHMEG_00017893
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.
    
 0.589
PHMEG_00010692
Uncharacterized protein.
    
 0.589
PHMEG_0004851
Ubiquitin activating enzyme.
    
 0.589
PHMEG_00010270
Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.586
Your Current Organism:
Phytophthora megakarya
NCBI taxonomy Id: 4795
Other names: ATCC 42100, CBS 238.83, IMI 202077, P. megakarya
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