| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKI98722.1 | AKJ01374.1 | AA314_00349 | AA314_03000 | ROK family Glucokinase. | Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. | 0.920 |
| AKI98722.1 | AKJ03373.1 | AA314_00349 | AA314_04999 | ROK family Glucokinase. | Mannose-6-phosphate isomerase. | 0.924 |
| AKI98722.1 | AKJ04915.1 | AA314_00349 | AA314_06541 | ROK family Glucokinase. | Fructokinase. | 0.912 |
| AKI98722.1 | AKJ05397.1 | AA314_00349 | AA314_07023 | ROK family Glucokinase. | PTS system, fructose-specific IIB component. | 0.937 |
| AKI98722.1 | AKJ06829.1 | AA314_00349 | AA314_08455 | ROK family Glucokinase. | Glucosamine-6-phosphate deaminase. | 0.917 |
| AKI98722.1 | AKJ07370.1 | AA314_00349 | AA314_08996 | ROK family Glucokinase. | Glucosamine-6-phosphate deaminase. | 0.916 |
| AKI98722.1 | glmS | AA314_00349 | AA314_02714 | ROK family Glucokinase. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.916 |
| AKI98722.1 | pfkA | AA314_00349 | AA314_08997 | ROK family Glucokinase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.912 |
| AKI98722.1 | pfp | AA314_00349 | AA314_02492 | ROK family Glucokinase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.912 |
| AKI98722.1 | pgi | AA314_00349 | AA314_01347 | ROK family Glucokinase. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.918 |
| AKJ01374.1 | AKI98722.1 | AA314_03000 | AA314_00349 | Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. | ROK family Glucokinase. | 0.920 |
| AKJ01374.1 | AKJ04915.1 | AA314_03000 | AA314_06541 | Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. | Fructokinase. | 0.930 |
| AKJ03373.1 | AKI98722.1 | AA314_04999 | AA314_00349 | Mannose-6-phosphate isomerase. | ROK family Glucokinase. | 0.924 |
| AKJ03373.1 | AKJ04915.1 | AA314_04999 | AA314_06541 | Mannose-6-phosphate isomerase. | Fructokinase. | 0.916 |
| AKJ03373.1 | AKJ05397.1 | AA314_04999 | AA314_07023 | Mannose-6-phosphate isomerase. | PTS system, fructose-specific IIB component. | 0.724 |
| AKJ03373.1 | AKJ06829.1 | AA314_04999 | AA314_08455 | Mannose-6-phosphate isomerase. | Glucosamine-6-phosphate deaminase. | 0.912 |
| AKJ03373.1 | AKJ07370.1 | AA314_04999 | AA314_08996 | Mannose-6-phosphate isomerase. | Glucosamine-6-phosphate deaminase. | 0.909 |
| AKJ03373.1 | glmS | AA314_04999 | AA314_02714 | Mannose-6-phosphate isomerase. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.929 |
| AKJ03373.1 | pfkA | AA314_04999 | AA314_08997 | Mannose-6-phosphate isomerase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.916 |
| AKJ03373.1 | pfp | AA314_04999 | AA314_02492 | Mannose-6-phosphate isomerase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.916 |
