node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKI98541.1 | AKJ01681.1 | AA314_00168 | AA314_03307 | Ribulose-5-phosphate 4-epimerase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.642 |
AKI98541.1 | AKJ05397.1 | AA314_00168 | AA314_07023 | Ribulose-5-phosphate 4-epimerase. | PTS system, fructose-specific IIB component. | 0.456 |
AKI98541.1 | AKJ05939.1 | AA314_00168 | AA314_07565 | Ribulose-5-phosphate 4-epimerase. | Hypothetical protein. | 0.696 |
AKI98541.1 | AKJ06845.1 | AA314_00168 | AA314_08471 | Ribulose-5-phosphate 4-epimerase. | Hydroxymethylglutaryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 0.696 |
AKI98541.1 | AKJ07588.1 | AA314_00168 | AA314_09214 | Ribulose-5-phosphate 4-epimerase. | Xylulose kinase. | 0.640 |
AKI98541.1 | mtnA | AA314_00168 | AA314_00167 | Ribulose-5-phosphate 4-epimerase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.968 |
AKI98541.1 | mtnB | AA314_00168 | AA314_01127 | Ribulose-5-phosphate 4-epimerase. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.589 |
AKI98541.1 | mtnD | AA314_00168 | AA314_01128 | Ribulose-5-phosphate 4-epimerase. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.625 |
AKI99499.1 | mtnB | AA314_01126 | AA314_01127 | Hypothetical protein. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.612 |
AKI99499.1 | mtnC | AA314_01126 | AA314_01129 | Hypothetical protein. | 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.605 |
AKI99499.1 | mtnD | AA314_01126 | AA314_01128 | Hypothetical protein. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.605 |
AKJ01681.1 | AKI98541.1 | AA314_03307 | AA314_00168 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribulose-5-phosphate 4-epimerase. | 0.642 |
AKJ01681.1 | mtnA | AA314_03307 | AA314_00167 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.763 |
AKJ01681.1 | mtnB | AA314_03307 | AA314_01127 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.642 |
AKJ01681.1 | mtnD | AA314_03307 | AA314_01128 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.704 |
AKJ05397.1 | AKI98541.1 | AA314_07023 | AA314_00168 | PTS system, fructose-specific IIB component. | Ribulose-5-phosphate 4-epimerase. | 0.456 |
AKJ05397.1 | AKJ05939.1 | AA314_07023 | AA314_07565 | PTS system, fructose-specific IIB component. | Hypothetical protein. | 0.457 |
AKJ05397.1 | AKJ06845.1 | AA314_07023 | AA314_08471 | PTS system, fructose-specific IIB component. | Hydroxymethylglutaryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. | 0.457 |
AKJ05397.1 | AKJ07588.1 | AA314_07023 | AA314_09214 | PTS system, fructose-specific IIB component. | Xylulose kinase. | 0.447 |
AKJ05397.1 | mtnB | AA314_07023 | AA314_01127 | PTS system, fructose-specific IIB component. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.456 |