| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKI99579.1 | AKI99644.1 | AA314_01206 | AA314_01271 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Citrate synthase. | 0.961 |
| AKI99579.1 | AKJ00286.1 | AA314_01206 | AA314_01912 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Acetyl-coenzyme A synthetase. | 0.601 |
| AKI99579.1 | AKJ01038.1 | AA314_01206 | AA314_02664 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.601 |
| AKI99579.1 | AKJ01041.1 | AA314_01206 | AA314_02667 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.716 |
| AKI99579.1 | AKJ06795.1 | AA314_01206 | AA314_08421 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.601 |
| AKI99579.1 | AKJ07449.1 | AA314_01206 | AA314_09075 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate synthase; Belongs to the malate synthase family. | 0.933 |
| AKI99579.1 | fumC | AA314_01206 | AA314_09070 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.971 |
| AKI99579.1 | mdh | AA314_01206 | AA314_05041 | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.990 |
| AKI99644.1 | AKI99579.1 | AA314_01271 | AA314_01206 | Citrate synthase. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.961 |
| AKI99644.1 | AKJ00286.1 | AA314_01271 | AA314_01912 | Citrate synthase. | Acetyl-coenzyme A synthetase. | 0.936 |
| AKI99644.1 | AKJ01038.1 | AA314_01271 | AA314_02664 | Citrate synthase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.936 |
| AKI99644.1 | AKJ01041.1 | AA314_01271 | AA314_02667 | Citrate synthase. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.997 |
| AKI99644.1 | AKJ04577.1 | AA314_01271 | AA314_06203 | Citrate synthase. | Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. | 0.968 |
| AKI99644.1 | AKJ05458.1 | AA314_01271 | AA314_07084 | Citrate synthase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.968 |
| AKI99644.1 | AKJ06795.1 | AA314_01271 | AA314_08421 | Citrate synthase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.936 |
| AKI99644.1 | AKJ07449.1 | AA314_01271 | AA314_09075 | Citrate synthase. | Malate synthase; Belongs to the malate synthase family. | 0.961 |
| AKI99644.1 | fumC | AA314_01271 | AA314_09070 | Citrate synthase. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.965 |
| AKI99644.1 | mdh | AA314_01271 | AA314_05041 | Citrate synthase. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.982 |
| AKJ00286.1 | AKI99579.1 | AA314_01912 | AA314_01206 | Acetyl-coenzyme A synthetase. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.601 |
| AKJ00286.1 | AKI99644.1 | AA314_01912 | AA314_01271 | Acetyl-coenzyme A synthetase. | Citrate synthase. | 0.936 |