node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKI99804.1 | queE | AA314_01431 | AA314_01430 | NADH pyrophosphatase. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.483 |
AKJ00872.1 | queE | AA314_02498 | AA314_01430 | LSU m3Psi1915 methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.470 |
AKJ03862.1 | AKJ05095.1 | AA314_05488 | AA314_06721 | 6-carboxytetrahydropterin synthase. | GTP cyclohydrolase I. | 0.988 |
AKJ03862.1 | guaA | AA314_05488 | AA314_05475 | 6-carboxytetrahydropterin synthase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.425 |
AKJ03862.1 | queC | AA314_05488 | AA314_09005 | 6-carboxytetrahydropterin synthase. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.959 |
AKJ03862.1 | queE | AA314_05488 | AA314_01430 | 6-carboxytetrahydropterin synthase. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.990 |
AKJ03862.1 | queF | AA314_05488 | AA314_08886 | 6-carboxytetrahydropterin synthase. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.877 |
AKJ05095.1 | AKJ03862.1 | AA314_06721 | AA314_05488 | GTP cyclohydrolase I. | 6-carboxytetrahydropterin synthase. | 0.988 |
AKJ05095.1 | AKJ06979.1 | AA314_06721 | AA314_08605 | GTP cyclohydrolase I. | Epoxyqueuosine. | 0.427 |
AKJ05095.1 | queE | AA314_06721 | AA314_01430 | GTP cyclohydrolase I. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.512 |
AKJ06979.1 | AKJ05095.1 | AA314_08605 | AA314_06721 | Epoxyqueuosine. | GTP cyclohydrolase I. | 0.427 |
AKJ06979.1 | queC | AA314_08605 | AA314_09005 | Epoxyqueuosine. | Queuosine Biosynthesis QueC ATPase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.472 |
AKJ06979.1 | queE | AA314_08605 | AA314_01430 | Epoxyqueuosine. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.406 |
AKJ06979.1 | queF | AA314_08605 | AA314_08886 | Epoxyqueuosine. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.510 |
guaA | AKJ03862.1 | AA314_05475 | AA314_05488 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 6-carboxytetrahydropterin synthase. | 0.425 |
guaA | purF | AA314_05475 | AA314_02310 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.772 |
guaA | queE | AA314_05475 | AA314_01430 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.445 |
guaA | queF | AA314_05475 | AA314_08886 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | NADPH dependent preQ0 reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.471 |
purF | guaA | AA314_02310 | AA314_05475 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.772 |
purF | queE | AA314_02310 | AA314_01430 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | Queuosine Biosynthesis QueE Radical SAM; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.491 |