Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (498 aa)    
Predicted Functional Partners:
AKJ00805.1
Hypothetical protein.
 
     0.953
AKJ00801.1
Hypothetical protein.
 
     0.934
mtnP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
     
 0.907
AKJ05043.1
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.902
AKJ01006.1
S-adenosylhomocysteine deaminase.
     
  0.900
AKJ02856.1
Agmatinase; Belongs to the arginase family.
     
  0.900
AKJ06549.1
S-adenosylhomocysteine deaminase.
     
  0.900
AKJ00803.1
Hypothetical protein.
       0.721
AKJ00802.1
Hypothetical protein.
       0.682
speA
Biosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine.
     
  0.500
Your Current Organism:
Archangium gephyra
NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis
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