node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ00993.1 | AKJ00994.1 | AA314_02619 | AA314_02620 | Glutamine amidotransferase class-I. | Hypothetical protein. | 0.752 |
AKJ00993.1 | AKJ01732.1 | AA314_02619 | AA314_03358 | Glutamine amidotransferase class-I. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.907 |
AKJ00993.1 | AKJ02152.1 | AA314_02619 | AA314_03778 | Glutamine amidotransferase class-I. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.918 |
AKJ00993.1 | AKJ02567.1 | AA314_02619 | AA314_04193 | Glutamine amidotransferase class-I. | Nucleoside triphosphate pyrophosphohydrolase MazG. | 0.900 |
AKJ00993.1 | AKJ03886.1 | AA314_02619 | AA314_05512 | Glutamine amidotransferase class-I. | Inosine-5'-monophosphate dehydrogenase. | 0.955 |
AKJ00993.1 | AKJ05351.1 | AA314_02619 | AA314_06977 | Glutamine amidotransferase class-I. | Xanthosine/inosine triphosphate pyrophosphatase. | 0.907 |
AKJ00993.1 | AKJ05468.1 | AA314_02619 | AA314_07094 | Glutamine amidotransferase class-I. | 5'-nucleotidase. | 0.703 |
AKJ00993.1 | apt | AA314_02619 | AA314_03517 | Glutamine amidotransferase class-I. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.934 |
AKJ00993.1 | gmk | AA314_02619 | AA314_04237 | Glutamine amidotransferase class-I. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.919 |
AKJ00993.1 | guaB | AA314_02619 | AA314_05477 | Glutamine amidotransferase class-I. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.980 |
AKJ00994.1 | AKJ00993.1 | AA314_02620 | AA314_02619 | Hypothetical protein. | Glutamine amidotransferase class-I. | 0.752 |
AKJ01732.1 | AKJ00993.1 | AA314_03358 | AA314_02619 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine amidotransferase class-I. | 0.907 |
AKJ01732.1 | AKJ02152.1 | AA314_03358 | AA314_03778 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.907 |
AKJ01732.1 | AKJ03886.1 | AA314_03358 | AA314_05512 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase. | 0.930 |
AKJ01732.1 | AKJ05351.1 | AA314_03358 | AA314_06977 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Xanthosine/inosine triphosphate pyrophosphatase. | 0.920 |
AKJ01732.1 | AKJ05468.1 | AA314_03358 | AA314_07094 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 5'-nucleotidase. | 0.650 |
AKJ01732.1 | guaB | AA314_03358 | AA314_05477 | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.929 |
AKJ02152.1 | AKJ00993.1 | AA314_03778 | AA314_02619 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Glutamine amidotransferase class-I. | 0.918 |
AKJ02152.1 | AKJ01732.1 | AA314_03778 | AA314_03358 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Nucleoside 5-triphosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.907 |
AKJ02152.1 | AKJ02567.1 | AA314_03778 | AA314_04193 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Nucleoside triphosphate pyrophosphohydrolase MazG. | 0.926 |