node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKI99283.1 | AKI99850.1 | AA314_00910 | AA314_01477 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase III. | 0.975 |
AKI99283.1 | AKJ01409.1 | AA314_00910 | AA314_03035 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase UvrD/PcrA. | 0.701 |
AKI99283.1 | AKJ06673.1 | AA314_00910 | AA314_08299 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DinG family ATP-dependent helicase YoaA. | 0.761 |
AKI99283.1 | AKJ06742.1 | AA314_00910 | AA314_08368 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III alpha subunit. | 0.987 |
AKI99283.1 | polA | AA314_00910 | AA314_06530 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.996 |
AKI99283.1 | recR | AA314_00910 | AA314_03213 | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.590 |
AKI99850.1 | AKI99283.1 | AA314_01477 | AA314_00910 | DNA topoisomerase III. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.975 |
AKI99850.1 | AKJ01409.1 | AA314_01477 | AA314_03035 | DNA topoisomerase III. | ATP-dependent DNA helicase UvrD/PcrA. | 0.948 |
AKI99850.1 | AKJ05136.1 | AA314_01477 | AA314_06762 | DNA topoisomerase III. | Excinuclease ABC subunit C. | 0.428 |
AKI99850.1 | AKJ06673.1 | AA314_01477 | AA314_08299 | DNA topoisomerase III. | DinG family ATP-dependent helicase YoaA. | 0.977 |
AKI99850.1 | AKJ06742.1 | AA314_01477 | AA314_08368 | DNA topoisomerase III. | DNA polymerase III alpha subunit. | 0.461 |
AKI99850.1 | polA | AA314_01477 | AA314_06530 | DNA topoisomerase III. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
AKI99850.1 | radA | AA314_01477 | AA314_02517 | DNA topoisomerase III. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.404 |
AKI99850.1 | recR | AA314_01477 | AA314_03213 | DNA topoisomerase III. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.468 |
AKI99850.1 | uvrB | AA314_01477 | AA314_07137 | DNA topoisomerase III. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.422 |
AKI99850.1 | uvrC | AA314_01477 | AA314_07136 | DNA topoisomerase III. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.428 |
AKJ01409.1 | AKI99283.1 | AA314_03035 | AA314_00910 | ATP-dependent DNA helicase UvrD/PcrA. | DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.701 |
AKJ01409.1 | AKI99850.1 | AA314_03035 | AA314_01477 | ATP-dependent DNA helicase UvrD/PcrA. | DNA topoisomerase III. | 0.948 |
AKJ01409.1 | AKJ05136.1 | AA314_03035 | AA314_06762 | ATP-dependent DNA helicase UvrD/PcrA. | Excinuclease ABC subunit C. | 0.640 |
AKJ01409.1 | AKJ06673.1 | AA314_03035 | AA314_08299 | ATP-dependent DNA helicase UvrD/PcrA. | DinG family ATP-dependent helicase YoaA. | 0.596 |