Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKJ01433.1DNA topoisomerase III. (109 aa)    
Predicted Functional Partners:
AKJ05957.1
SET domain protein.
 
 
 
 0.648
AKI99850.1
DNA topoisomerase III.
 
  
   0.623
AKJ03441.1
DNA topoisomerase IB.
    
 
 0.562
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.499
AKJ05739.1
Topoisomerase IV subunit B.
    
 
 0.499
AKJ01432.1
UDP-glucose 4-epimerase.
       0.496
AKJ01434.1
Malto-oligosyltrehalose synthase.
       0.446
AKJ01435.1
Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family.
       0.446
AKJ01428.1
Long-chain-fatty-acid CoA ligase.
  
 
 0.404
Your Current Organism:
Archangium gephyra
NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis
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