Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKJ01681.15-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1152 aa)    
Predicted Functional Partners:
AKJ04992.1
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.997
AKJ01627.1
O-acetylhomoserine sulfhydrylase.
  
 
 0.962
AKJ05002.1
Cystathionine beta-lyase.
  
 
 0.962
AKJ05003.1
Cystathionine gamma-synthase.
  
 
 0.962
AKJ05220.1
O-acetylhomoserine sulfhydrylase.
  
 
 0.962
AKJ06319.1
Cystathionine gamma-lyase.
  
 
 0.962
AKJ06906.1
O-acetylhomoserine sulfhydrylase.
  
 
 0.952
AKJ05005.1
Aspartokinase.
  
 
 0.951
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.949
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.947
Your Current Organism:
Archangium gephyra
NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.