node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKJ01894.1 | AKJ04225.1 | AA314_03520 | AA314_05851 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein. | 0.651 |
AKJ01894.1 | lexA | AA314_03520 | AA314_04464 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.796 |
AKJ01894.1 | mfd | AA314_03520 | AA314_02107 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.693 |
AKJ01894.1 | nadK | AA314_03520 | AA314_03510 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.808 |
AKJ01894.1 | recA | AA314_03520 | AA314_02723 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.747 |
AKJ01894.1 | recA-2 | AA314_03520 | AA314_02892 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.766 |
AKJ01894.1 | recF | AA314_03520 | AA314_00925 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.583 |
AKJ01894.1 | recX-2 | AA314_03520 | AA314_03351 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.581 |
AKJ01894.1 | ruvA | AA314_03520 | AA314_03882 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.663 |
AKJ01894.1 | xseA | AA314_03520 | AA314_04315 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.566 |
AKJ04225.1 | AKJ01894.1 | AA314_05851 | AA314_03520 | RecA protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.651 |
AKJ04225.1 | lexA | AA314_05851 | AA314_04464 | RecA protein. | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.900 |
AKJ04225.1 | recA | AA314_05851 | AA314_02723 | RecA protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.928 |
AKJ04225.1 | recA-2 | AA314_05851 | AA314_02892 | RecA protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.928 |
AKJ04225.1 | recX-2 | AA314_05851 | AA314_03351 | RecA protein. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.727 |
AKJ04225.1 | ruvA | AA314_05851 | AA314_03882 | RecA protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.462 |
lexA | AKJ01894.1 | AA314_04464 | AA314_03520 | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.796 |
lexA | AKJ04225.1 | AA314_04464 | AA314_05851 | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | RecA protein. | 0.900 |
lexA | mfd | AA314_04464 | AA314_02107 | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.486 |
lexA | recA | AA314_04464 | AA314_02723 | SOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.974 |