AKJ01929.1 protein (Archangium gephyra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

AKJ01929.1

Sulfate permease; Belongs to the heat shock protein 70 family. (616 aa)

Predicted Functional Partners:

AKJ01930.1

0.942

dnaJ

0.861

groS

0.772

hscB

0.753

groL

0.749

groL-2

0.749

grpE

0.746

grpE-2

0.746

AKJ01144.1

0.738

AKJ05633.1

0.738

Your Current Organism:

Archangium gephyra

NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKJ01144.1	AKJ01929.1	AA314_02770	AA314_03555	Chaperone protein HtpG.	Sulfate permease; Belongs to the heat shock protein 70 family.	0.738
AKJ01144.1	AKJ05633.1	AA314_02770	AA314_07259	Chaperone protein HtpG.	Putative heat shock protein, hsp90-family.	0.927
AKJ01144.1	dnaJ	AA314_02770	AA314_01674	Chaperone protein HtpG.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.836
AKJ01144.1	groL	AA314_02770	AA314_03948	Chaperone protein HtpG.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.796
AKJ01144.1	groL-2	AA314_02770	AA314_04441	Chaperone protein HtpG.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.796
AKJ01144.1	groS	AA314_02770	AA314_03949	Chaperone protein HtpG.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.747
AKJ01144.1	grpE	AA314_02770	AA314_06266	Chaperone protein HtpG.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.594
AKJ01144.1	grpE-2	AA314_02770	AA314_09392	Chaperone protein HtpG.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.594
AKJ01929.1	AKJ01144.1	AA314_03555	AA314_02770	Sulfate permease; Belongs to the heat shock protein 70 family.	Chaperone protein HtpG.	0.738
AKJ01929.1	AKJ01930.1	AA314_03555	AA314_03556	Sulfate permease; Belongs to the heat shock protein 70 family.	Hypothetical protein.	0.942
AKJ01929.1	AKJ05633.1	AA314_03555	AA314_07259	Sulfate permease; Belongs to the heat shock protein 70 family.	Putative heat shock protein, hsp90-family.	0.738
AKJ01929.1	dnaJ	AA314_03555	AA314_01674	Sulfate permease; Belongs to the heat shock protein 70 family.	Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]	0.861
AKJ01929.1	groL	AA314_03555	AA314_03948	Sulfate permease; Belongs to the heat shock protein 70 family.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.749
AKJ01929.1	groL-2	AA314_03555	AA314_04441	Sulfate permease; Belongs to the heat shock protein 70 family.	Heat shock protein 60 family chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.	0.749
AKJ01929.1	groS	AA314_03555	AA314_03949	Sulfate permease; Belongs to the heat shock protein 70 family.	Heat shock protein 60 family co-chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.772
AKJ01929.1	grpE	AA314_03555	AA314_06266	Sulfate permease; Belongs to the heat shock protein 70 family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.746
AKJ01929.1	grpE-2	AA314_03555	AA314_09392	Sulfate permease; Belongs to the heat shock protein 70 family.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.746
AKJ01929.1	hscB	AA314_03555	AA314_03823	Sulfate permease; Belongs to the heat shock protein 70 family.	Chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.	0.753
AKJ01930.1	AKJ01929.1	AA314_03556	AA314_03555	Hypothetical protein.	Sulfate permease; Belongs to the heat shock protein 70 family.	0.942
AKJ05633.1	AKJ01144.1	AA314_07259	AA314_02770	Putative heat shock protein, hsp90-family.	Chaperone protein HtpG.	0.927