Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AKJ02181.1Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex. (294 aa)    
Predicted Functional Partners:
AKJ02752.1
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit.
 
 0.977
AKJ05459.1
Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.961
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.931
AKJ07087.1
2-oxoglutarate dehydrogenase E1 component.
 
 0.922
AKJ02753.1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit.
 
 0.914
AKJ04580.1
Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase.
 
 0.889
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.784
AKJ05363.1
PF00070 family, FAD-dependent NAD(P)-disulfide oxidoreductase.
 
 0.771
AKI98593.1
Glutathione reductase; Maintains high levels of reduced glutathione.
  
 0.739
AKJ00405.1
Soluble pyridine nucleotide transhydrogenase.
  
 0.739
Your Current Organism:
Archangium gephyra
NCBI taxonomy Id: 48
Other names: A. gephyra, ATCC 25201, Chondrococcus cerebriformis, Chondromyces serpens, DSM 2261, Myxococcus cerebriformis
Server load: low (12%) [HD]